Publications

Spotlight Publication

Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

American Society for Clinical Oncology (ASCO) GI

Jan 18
- Jan 20, 2024
Neoadjuvant botensilimab plus balstilimab (BOT/BAL) in resectable mismatch repair proficient and deficient colorectal cancer: NEST-1 clinical trial.
Kasi, et. al.

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QS-21 STIMULON™ Adjuvant

Vaccine

Feb 28, 2001
QS-21 Promotes an Adjuvant Effect Allowing for Reduced Antigen Dose During HIV-1 Envelope Subunit Immunization in Human.
Evans, et al.
QS-21 STIMULON™ Adjuvant

The Journal of Immunology

Feb 15, 2001
Oral QS-21 Requires Early IL-4 Help for Induction of Mucosal and Systemic Immunity.
Boyaka, et al.
QS-21 STIMULON™ Adjuvant

Clinical Cancer Research

May 1, 2002
T-cell Responses Against Tyrosinase 368-376(370D) Peptide in HLA*A0201+ Melanoma Patients: Randomized Trial Comparing Incomplete Freund’s Adjuvant, Granulocyte Macrophage Colony-Stimulating Factor, and QS-21 as Immunological Adjuvants.
Schaed, et al.
QS-21 STIMULON™ Adjuvant

The Journal of Immunology

Jul 15, 2005
Induction of Humoral and CD8+ T Cell Responses are Required for Protection Against Lethal Ebola Virus Infection.
Warfiled, et. al.
QS-21 STIMULON™ Adjuvant

Vaccine

Mar 4, 2008
Vaccine Adjuvant Systems Containing Monophosphoryl Lipid A and QS21 Induce Strong and Persistent Humoral and T Cell Responses Against Hepatitis B Surface Antigen in Healthy Adult Volunteers.
Vandepapelière, et al.
QS-21 STIMULON™ Adjuvant

Expert Opinion on Biological Therapy

Jun 12, 2008
Cancer Immunotherapy Targeting Tumour-Specific Antigens: Towards a New Therapy for Minimal Residual Disease.
Brichard, et al.
QS-21 STIMULON™ Adjuvant

New England Journal of Medicine

Dec 11, 2008
Efficacy of RTS,S/AS01E Vaccine Against Malaria in Children 5 to 17 Months of Age.
Bejon, et al.
QS-21 STIMULON™ Adjuvant

New England Journal of Medicine

Dec 11, 2008
Safety and Immunogenicity of RTS,S/AS02D Malaria Vaccine in Infants.
Abdulla, et al.
QS-21 STIMULON™ Adjuvant

Kidney International

Feb 1, 2010
Rapid, Enhanced, and Persistent Protection of Patients with Renal Insufficiency by AS02(V)-Adjuvanted Hepatitis B Vaccine.
Surquin, et al.
QS-21 STIMULON™ Adjuvant

Vaccine

Nov 3, 2011
A Heat Shock Protein Based Polyvalent Vaccine Targeting HSV-2: CD4(+) and CD8(+) Cellular Immunity and Protective Efficacy.
Mo, et al.
QS-21 STIMULON™ Adjuvant

Vaccine

Nov 3, 2011
Safety and Immunogenicity of Long HSV-2 Peptides Complexed with rhHsc70 in HSV-2 Seropositive Persons.
Wald, et al.
QS-21 STIMULON™ Adjuvant

The Lancet Infectious Diseases

Oct 1, 2011
Safety and Efficacy of the RTS,S/AS01E Candidate Malaria Vaccine Given With Expanded-Programme-On-Immunisation Vaccines: 19 Month Follow-Up of a Randomised, Open-Label, Phase 2 Trial.
Asante, et al.