Publications

Spotlight Publication

Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

American Society of Clinical Oncology (ASCO) GI

Jan 18
- Jan 20, 2024
Neoadjuvant botensilimab plus balstilimab (BOT/BAL) in resectable mismatch repair proficient and deficient colorectal cancer: NEST-1 clinical trial.
Kasi, et. al.

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Society for Immunotherapy of Cancer (SITC)

Nov 9
- Nov 14, 2020
Beyond PD-L1: novel PD-1 biomarkers identified by driving T cell dysfunction in vitro.
Pabla, et al.
QS-21 STIMULON™ Adjuvant

The Journal of Immunology

Jan 15, 1991
Separation and Characterization of Saponins With Adjuvant Activity From Quillaja Saponaria Molina Cortex.
Kensil, CR.
QS-21 STIMULON™ Adjuvant

The Journal of Immunology

Apr 15, 1992
Saponin Adjuvant Induction of Ovalbumin-Specific CD8+ Cytotoxic T Lymphocyte Responses.
Newman, et al.
QS-21 STIMULON™ Adjuvant

Critical Reviews in Therapeutic Drug Carrier Systems

Jan 1, 1996
Saponins as Vaccine Adjuvants.
Kensil, CR.
QS-21 STIMULON™ Adjuvant

Cancer Research

Jul 1, 1995
GM2-KLH Conjugate Vaccine: Increased Immunogenicity in Melanoma Patients After Administration With Immunological Adjuvant QS-21.
Helling, et al.
QS-21 STIMULON™ Adjuvant

Carbohydrate Research

Jan 4, 1996
Structure of the saponin adjuvant QS-21 and its Base-Catalyzed Isomerization Product by 1H and Natural Abundance 13C NMR Spectroscopy.
Jacobsen, et al.
QS-21 STIMULON™ Adjuvant

New England Journal of Medicine

Jan 9, 1997
A Preliminary Evaluation of a Recombinant Circumsporozoite Protein Vaccine Against Plasmodium Falciparum Malaria. RTS,S Malaria Vaccine Evaluation Group.
Stoute, et al.
QS-21 STIMULON™ Adjuvant

Journal of Virology

Jun 1, 1998
Induction of Systemic and Mucosal Immune Responses to Human Immunodeficiency Virus Type 1 by a DNA Vaccine Formulated With QS-21 Saponin Adjuvant via Intramuscular and Intranasal Routes.
Sasaki, et al.
QS-21 STIMULON™ Adjuvant

Vaccine

Nov 12, 1999
Comparison of the Effect of Different Immunological Adjuvants on the Antibody and T Cell Response to Immunization with MUC1-KLH and GD3-KLH Conjugate Cancer Vaccines.
Kim, et al.
QS-21 STIMULON™ Adjuvant

The Journal of Infectious Diseases

Nov 1, 2009
Synthetic Malaria Peptide Vaccine Elicits High Levels of Antibodies in Vaccinees of Defined HLA Genotypes.
Nardin, et al.
QS-21 STIMULON™ Adjuvant

Vaccine

Jul 16, 2001
Three Double-Blind, Randomized Trials Evaluating the Safety and Tolerance of Different Formulations of the Saponin Adjuvant QS-21.
Waite, et al.
QS-21 STIMULON™ Adjuvant

Vaccine

Feb 28, 2001
QS-21 Promotes an Adjuvant Effect Allowing for Reduced Antigen Dose During HIV-1 Envelope Subunit Immunization in Human.
Evans, et al.