Publications

Spotlight Publication

Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

American Society of Clinical Oncology (ASCO) GI

Jan 18
- Jan 20, 2024
Neoadjuvant botensilimab plus balstilimab (BOT/BAL) in resectable mismatch repair proficient and deficient colorectal cancer: NEST-1 clinical trial.
Kasi, et. al.

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Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

American Society of Clinical Oncology (ASCO) GI

Jan 18
- Jan 20, 2024
Neoadjuvant botensilimab plus balstilimab (BOT/BAL) in resectable mismatch repair proficient and deficient colorectal cancer: NEST-1 clinical trial.
Kasi, et. al.
Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Oncoimmunology

Nov 5, 2023
Next-generation CTLA-4 targeting molecules and combination therapy: promising strategies for improving cancer immunotherapy
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

European Society for Medical Oncology (ESMO)

Oct 21, 2023
Efficacy and safety of botensilimab plus balstilimab in patients with refractory metastatic sarcoma
Wilky, et al.
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Connective Tissue Oncology Society (CTOS)

Oct 13, 2023
Efficacy and safety of Botensilimab plus Balstilimab combination therapy in refractory metastatic sarcoma patients: findings from an ongoing expanded phase 1b study
Wilky, et al.
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Oncogene

Sep 21, 2023
Neoadjuvant botensilimab plus balstilimab response pattern in locally advanced mismatch repair proficient colorectal cancer
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

European Society for Medical Oncology (ESMO) GI

Jun 28
- Jul 1, 2023
Results from an expanded phase 1 trial of botensilimab, a multifunctional anti-CTLA-4, plus balstilimab(anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer
Bullock, et al.
Phosphopeptide Targets

Nature Communications

Jun 23, 2023
Molecular mechanism of phosphopeptide neoantigen immunogenicity
AGEN2373 (CD137 Agonist)

American Society of Clinical Oncology (ASCO)

Jun 3, 2023
A Phase 1 Study of AGEN2373, a Novel CD137 Agonist Antibody Designed to Avoid Hepatoxicity, in Patients with Advanced Solid Tumors
Barve et al.
Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Journal of Clinical Oncology

Apr 11, 2023
Accelerating the Evolution of Immune-Related Enterocolitis Management
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Society of Gynecologic Oncology (SGO)

Mar 27, 2023
Botensilimab, a novel innate/adaptive immune activator, plus balstilimab(anti-PD-1) in patients with recurrent platinum refractory/resistant ovarian cancer
Bockorny B, et al.
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

American Society of Clinical Oncology (ASCO) GI

Jan 21, 2023
Results from a phase 1a/1b study of botensilimab (BOT), a novel innate/adaptive immune activator, plus balstilimab (BAL; anti-PD-1 antibody) in metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)
El-Khoueiry, et al.
Balstilimab (PD-1 Antagonist), Botensilimab (Fc-Enhanced CTLA-4 Antagonist)

Connective Tissue Oncology Society (CTOS)

Nov 18, 2022
A Phase IA/IB study of Botensilimab, a novel innate/adaptive immune activator, plus Balstilimab for the treatment of patients with sarcoma
Wilky, et al.