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Botensilimab (Fc-enhanced anti-CTLA-4)
Balstilimab (PD-1 inhibitor)
Systemic and Tumor-Microenvironment Inflammation Shape Outcomes in Patients with Immunologically Cold, Treatment-Refractory Tumors Treated with Fc-Enhanced Anti–CTLA-4 Botensilimab
AACR
American Association for Cancer Research Immuno-Oncology (AACR-IO)
February 19, 2026
,
Delepine, C. et al.
Colorectal (CRC)
Ovarian
Sarcoma
Lung
Other
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Botensilimab (Fc-enhanced anti-CTLA-4)
Balstilimab (PD-1 inhibitor)
Botensilimab (Fc-enhanced anti–CTLA-4 antibody) plus balstilimab (anti–PD-1 antibody) in patients with treatment-refractory ovarian cancer
Other Articles & Publications
Journal for ImmunoTherapy of Cancer (JITC)
December 23, 2025
,
Porter, et al.
Ovarian
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Balstilimab (PD-1 inhibitor)
Botensilimab (Fc-enhanced anti-CTLA-4)
New Era of CTLA-4 Modulation
ESMO
European Society for Medical Oncology, Immuno-Oncology (ESMO-IO)
December 11, 2025
,
O’Day, et al.
Colorectal (CRC)
Lung
Ovarian
Carcinoma
Sarcoma
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Balstilimab (PD-1 inhibitor)
Zalifrelimab (CTLA-4 Antagonist)
Efficacy and safety of balstilimab with or without zalfrelimab in recurrent cervical cancer: Results from the global phase 2 RaPiDs trial (GOG-3028)