Dr. Robert Stein has over 35 years of experience and accomplishments in the pharmaceutical and biotech industry and advises Agenus’ global research and development efforts. Bob previously served as the Company’s President of R&D. Over the course of his career, Bob has played a significant role in the discovery and development of eight marketed drugs, including Sustiva®, Fablyn®, Viviant®, PanRetin®, TargRetin®, Promacta®, & Eliquis®. Prior to working at Agenus, he held a number of progressively responsible senior management positions including Head of Pharmacology for Merck & Co., CSO & SVP of Research for Ligand Pharmaceuticals, EVP of Research & Preclinical Development for Dupont Merck, President and CSO for Incyte Pharmaceuticals, President of Roche Palo Alto, and CEO of KineMed. Bob spent the early part of his career at Merck, Sharp and Dohme Research Laboratories. He holds an MD and a PhD in Physiology & Pharmacology from Duke University.
Dr. Hagop Youssoufian brings more than 25 years of drug development expertise with specific experience in the development of protein-based therapeutics. Hagop has served in various senior roles in the pharmaceutical and biotechnology industry, including tenures as Chief Medical Officer at ImClone-Lilly and as President of R&D at Ziopharm and was involved in the development and approval of several oncology biologic products, including Erbitux® and Cyramza®. He is an elected member of the American Society for Clinical Investigation. Hagop received his Bachelor of Science from Boston College, his medical degree from the University of Massachusetts Medical School and completed training in Internal Medicine and fellowship in Clinical Genetics at Johns Hopkins and in Hematology-Oncology at Massachusetts General Hospital. Hagop was a Visiting Scientist at Whitehead Institute with subsequent academic positions at Harvard Medical School and Baylor College of Medicine.
Dr. Curiel is a world-renowned physician-scientist and trained immunologist, past chief of hematology and medical oncology and executive director of an NCI-designated cancer center. Drs. Curiel in collaboration with Agenus’ Dr. John Castle, drive the translational and biomarker approaches to select patients most likely to benefit from combination approaches of our vaccines, adjuvants, and checkpoint modulating antibodies targeting T cells, tumor micro-environment conditioning, and regulatory T cell depletion strategies.